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Category Archives: Recommended Books

It’s time to admit that genes are not the blueprint for life

Nature: The view of biology often presented to the public is oversimplified and out of date. Scientists must set the record straight, argues a new book. How Life Works: A User’s Guide to the New Biology Philip Ball Pan Macmillan (2024) For too long, scientists have been content in espousing the lazy metaphor of living systems operating simply like machines, says science writer Philip Ball in How Life Works. Yet, it’s important to be open about the complexity of biology — including what we don’t know — because public understanding affects policy, health care and trust in science. “So long as we insist that cells are computers and genes are their code,” writes Ball, life might as well be “sprinkled with invisible magic”. But, reality “is far more interesting and wonderful”, as he explains in this must-read user’s guide for biologists and non-biologists alike. When the human genome was sequenced in 2001, many thought that it would prove to be an ‘instruction manual’ for life. But the genome turned out to be no blueprint. In fact, most genes don’t have a pre-set function that can be determined from their DNA sequence. Instead, genes’ activity — whether they are expressed or not, for instance, or the length of protein that they encode — depends on myriad external factors, from the diet to the environment in which the organism develops. And each trait can be influenced by many genes. For example, mutations in almost 300 genes have been identified as indicating a risk that a person will develop schizophrenia. It’s therefore a huge oversimplification, notes Ball, to say that genes cause this trait or that disease. The reality is that organisms are extremely robust, and a particular function can often be performed even when key genes are removed. For instance, although the HCN4 gene encodes a protein that acts as the heart’s primary pacemaker, the heart retains its rhythm even if the gene is mutated. Another metaphor that Ball criticizes is that of a protein with a fixed shape binding to its target being similar to how a key fits into a lock. Many proteins, he points out, have disordered domains — sections whose shape is not fixed, but changes constantly.”

Book Review: Transformative Negotiation Strategies for Everyday Change and Equitable Futures

Via LLRX – Book Review: Transformative Negotiation Strategies for Everyday Change and Equitable Futures – Jerry Lawson writes – So you think you know how to negotiate? You’ve done some deals, maybe a lot, maybe some for big bucks. Maybe attended some classes. Maybe read some books. Surely you can’t have all that much left to… Continue Reading

LLRX November 2023

The November 2023 issue of LLRX has 9 new articles and 6 new columns: AI in Banking and Finance, November 30, 2023 ; AI in Banking and Finance – November 16, 2023 – This semi-monthly column by Sabrina I. Pacifici highlights news, government reports, industry white papers, academic papers and speeches on the subject of AI’s… Continue Reading

A History of Bookmaking, From Scrolls to Scrolling

HyperAllergic: “If you’re shopping for the bibliophile on your list this holiday season (or you are said bibliophile), look no further! The Book by Design: The Remarkable Story of the World’s Greatest Invention (2023, University of Chicago Press) is an ambitious compendium that seeks to catalog and analyze the history of the book in myriad… Continue Reading

Hitting the Books: How the ‘Godfather of Cybercrime’ got his start on eBay

Engadget – “From bunk Beanie Babies to signal-stealing cable boxes, Brett Johnson has scammed them all. The internet has connected nearly everybody on the planet to a global network of information and influence, enabling humanity’s best and brightest minds unparalleled collaborative capabilities. At least that was the idea, more often than not these days, it… Continue Reading

This Is Why You Feel Existential Dread When You Open Instagram and TikTok

Gizmodo: “In Meganets: How Digital Forces Beyond Our Control Commandeer Our Daily Lives and Inner Realities, David Auerbach argues the the distinctly modern feeling of a loss of control over our lives is the result of these new online forces. The vast influence of Facebook, Google, TikTok, and other tech giants is neither in the… Continue Reading

When McKinsey Comes to Town: The Hidden Influence of the World’s Most Powerful Consulting Firm

London Review of Book, Laleh Khalili – “When McKinsey Comes to Town: The Hidden Influence of the World’s Most Powerful Consulting Firm by Walt Bogdanich and Michael Forsythe. Bodley Head, 354 pp., £20, October, 978 1 84792 625 8: “…Bogdanich and Forsythe’s​ book is a damning account of the way McKinsey has made workplaces unsafe, ditched consumer protections, disembowelled regulatory agencies,… Continue Reading

Data Cartels

Data Cartels The Companies That Control and Monopolize Our Information. Sarah Lamdan is Professor of Law at the City University of New York School of Law: “In our digital world, data is power. Information hoarding businesses reign supreme, using intimidation, aggression, and force to maintain influence and control. Sarah Lamdan brings us into the unregulated… Continue Reading

Restating the Law in the Shadow of Codes: The ALI in Its Formative Era, in The American Law Institute at 100: A Centennial History

DeMott, Deborah, Restating the Law in the Shadow of Codes: The ALI in Its Formative Era, in The American Law Institute at 100: A Centennial History (Andrew S. Gold & Robert W. Gordon eds) forthcoming 2023, Oxford University Press (August 28, 2022). Duke Law School Public Law & Legal Theory Series No. 2022-53, Available at… Continue Reading