TIME: “Which companies are shaping our future? That’s the question at the heart of our first ever TIME 100 Most Influential Companies, a new list—and an expansion of our iconic TIME100 franchise—that highlights businesses making an extraordinary impact around the world. To assemble it, TIME solicited nominations across sectors including health care, entertainment, transportation, technology and more from our global network of editors and correspondents, as well as from industry experts. Then, we evaluated each one on key factors, including relevance, impact, innovation, leadership, ambition and success. The result is a diverse array of 100 institutions, from the tech startup engineering a smarter way to recycle to the cryptocurrency firm reimagining the future of money to the pharma titans creating the vaccines of tomorrow (and today). Together, these businesses—and the leaders who steer them—are helping to chart an essential path forward.”