Dementia: Across the Lifespan & Around the Globe – “Alzheimer’s Disease International (ADI) estimates there will be over 131.5 million people living with dementia by 2050, as well as a shift in burden from the richest to poorest countries. These trends emphasize the need for a greater understanding of dementia from a global perspective. This PLOS Medicine Special Issue, guest edited by Carol Brayne and Bruce Miller, includes research articles, editorials, and perspectives that highlight the broad range of dementia research.”