The Atlantic: “We probably will need additional shots. But just how many depends on our immune systems, the virus, and how often they collide…A future of annual vaccinations would almost be a relief. In the past year, the U.S. government has recommended that almost everyone eligible be COVID-vaccinated three times over, and the possibility of an Omicron-focused shot now looms. But the sweet spot for boosting frequency isn’t all that easy to find—both undervaccinating and overvaccinating have downsides—and the narrative is definitely not as simple as more is more. Maybe we’ll luck out, and finagle some truly durable protection out of our current shots. Or perhaps we’re just at the start of what could be the world’s most intense and widespread repeat-vaccination campaign to date…

There are two main reasons to vaccinate the already vaccinated: a substantial drop in our body’s defenses or a huge hike in the virus’s offenses…”