“Today, the Presidential Commission for the Study of Bioethical Issues (Bioethics Commission) released the second volume of its two-part response to President Obama’s request related to the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Gray Matters: Topics at the Intersection of Neuroscience, Ethics, and Society, seeks to clarify the scientific landscape, identify common ground, and recommend ethical paths forward. Cautioning against hyperbole and misinformation when discussing the promise of neuroscience, the report offers 14 recommendations to help clear a path to productive discourse. “Alongside well-informed and well-intentioned discussion, when it comes to neuroscience, hyperbole and misinformation permeate the conversation,” Bioethics Commission Chair Amy Gutmann, Ph.D., said. “This exaggeration or hype can mislead the public, cause the misdirection of resources, and instill misplaced fears. It is easy to get carried away by exciting scientific frontiers and to lose sight of the fact that we are talking about people—not just colorful images of the brain.” With that in mind, the Bioethics Commission addresses three controversial topics in Gray Matters, Vol. 2 that have captured the public’s attention at the intersection of neuroscience, ethics, and society.  They are: cognitive enhancement, consent capacity, and neuroscience and the legal system. “There are many topics at this intersection, but these three are among the most hotly debated by scholars and the public alike and illustrate the ethical tensions and societal implications of advancing neuroscience and technology,” Gutmann added. “By collaborating with philosophers and ethicists, scientists will keep the full picture of personhood in view.” As part of the BRAIN Initiative, a White House Grand Challenge announced in April 2013, President Obama asked the Bioethics Commission to review the ethical issues associated with the conduct and implications of neuroscience research. In Gray Matters: Integrative Approaches for Neuroscience, Ethics, and Society, released in May 2014, the Commission focused on the importance of integrating ethics and neuroscience early and explicitly throughout the research endeavor. In Gray Matters, Vol. 2, the Bioethics Commission’s recommendations serve to guide the ethical progress of neuroscience and its applications. Commission recommendations are geared toward fostering informed conversations, and include:

• Prioritizing research into the treatment of neurological disorders, as well as research into existing low-technology strategies to improve neural health;
• Responsibly including participants with impaired consent capacity in research, with ethical protections in place;
• Avoiding overstatement or overreliance on neuroscientific evidence to draw legal conclusions.”